Revolutionizing Real-World Evidence practices in Europe
GREG – “Testing, improving, and co-creating Guidance and Tools for Real World Evidence Generation and Use for Decision-Making in Europe”, is a 60-month initiative that began in May 2025, funded by the Innovative Health Initiative Joint Undertaking (IHI JU). IHI supports collaborative research projects and builds networks of industrial and academic experts in order to boost health research and innovation in Europe. This Joint Undertaking receives support from the European Union’s Horizon Europe research and innovation programme and COCIR, EFPIA, Europa Bío, MedTech Europe, and Vaccines Europe.
GREG’s aim
The GREG project will create, pilot-test, and share practical, evidence-based guidance and tools to help generate and use Real-World Evidence (RWE). By improving how RWE informs the development and evaluation of medicines, medical devices, and drug-device combinations, GREG will support better decision-making for regulators and Health Technology Assessment (HTA) bodies.
GREG’s impact
The expertise behind GREG
The GREG public-private partnership has unique multidisciplinary strengths and encompasses leaders from key RWE European initiatives, including academia, regulators, HTA agencies, non-governmental organisations (NGOs), project management experts, and industry leaders from the medicines, medical devices, and drug-device sectors.
