News

WP2 is where regulatory science meets real-world practice. Co-Led by the University of Oxford, University of Edinburgh and Bayer, this work package engages regulators and stakeholders to co-create evidence-based best practice recommendations as well as tools for using Real-World Data (RWD) and Real-World Evidence (RWE) in regulatory decision-making for medicines, medical devices, and drug-device combinations....

Led by NICE (UK) and co-led by Medtronic, WP3 collaborates with Health Technology Assessment (HTA) bodies, payers, and industry to bridge the gap between Real-World Data (RWD) and its application in HTA, improving decision-making for medicines, medical devices, and drug-device combinations across Europe.  HTA bodies evaluate the clinical and economic value of health technologies, ensuring...

WP1 is the foundation of GREG, leading the co-creation of evidence-based practical guidance for the use of real-world data (RWD) and real-world evidence (RWE) in regulatory and health technology assessment (HTA) decision-making. Led by the Aragonese Institute of Health Sciences (IACS) and co-led by Novo Nordisk, this work package ensures that GREG’s outputs are scientifically...

The IHI-GREG project is excited to present a session at the upcoming in-person Patient Engagement Open Forum (PEOF), focusing on Real-World Data (RWD) and Real-World Evidence (RWE). This interactive workshop-style session will explore how to bridge knowledge gaps, build capacity among stakeholders to enhance the uptake of RWE, and ensure meaningful patient involvement in these...

Last week GREG held its annual Consortium Meeting in Copenhagen on 6–7th May 2026, bringing together partners from across the project to review progress, align on next steps, and strengthen collaboration. The meeting opened with an overview of achievements to date, including updates on use case selection and early lessons learned. Discussions highlighted the structured...

At the beginning of this week, GREG returned to Rotterdam for another international meeting, this time presenting at the OHDSI Europe Symposium 2026.  This event brings together global leaders in health data science, Real-World Evidence (RWE), and open-source collaboration. It was an excellent opportunity to share insights, foster partnerships, and explore innovative approaches to improving patient outcomes. The EHDEN...

Daniel Prieto-Alhambra (Erasmus MC), Tara Srouji (Novo Nordisk), and Annika Jödicke (University of Oxford) GREG’s Project Coordinator, Daniel Prieto-Alhambra, and Academic Co-Lead Annika Jödicke, took the stage at DIA Europe 2026 to present the project’s groundbreaking approach to real-world evidence (RWE) generation—highlighting how GREG is bridging the gap between real-world data and regulatory decision-making. As...

The meeting included 14 HTA experts that assess Real-World Evidence (RWE) submissions, generate national RWE to inform local pricing and reimbursement decisions, or work at a policy level to support RWE developments in HTA. These experts from across Europe and Canada contributed expertise relating to the use of RWE to support HTA of medicines, devices...

The GREG Consortium has taken part in the European Society of Cardiology (ESC) annual Congress, held in Madrid from August 29 to September 1, 2025. This event continues to be a cornerstone in the global cardiology calendar, bringing together thought leaders, clinicians, researchers, and regulators and policymakers from around the world to share knowledge, foster...

The GREG project officially commenced with a two-day Kick-Off Meeting held in Rotterdam on 14–15 May, where around 80 participants from academia, industry, regulatory bodies, and patient organisations took part. Supported by the Innovative Health Initiative (IHI JU), GREG aims to co-create and deliver evidence-based guidance and tools to support the generation and use of...

The GREG project has been officially launched to address persistent challenges in the generation, implementation, and acceptance of Real-World Evidence (RWE) for medicines, medical devices, and drug-device combinations in Europe. The GREG Initiative Will Tackle Persistent Challenges in Real-World Evidence While the interest and ability to use Real-World Data (RWD) sources to generate RWE have...